Spain’s startup scene has grown rapidly, with over 12,000 innovative companies emerging in various sectors, such as fintech, health tech, and e-commerce. The startup ecosystem in Spain reached an impressive milestone in 2024, securing over €4.5 billion in investments. This upward trend reflects the country’s increasing role in the global tech landscape, marked by a combination of government-backed initiatives, a skilled talent pool, and a focus on practical, scalable solutions in areas like mobility, logistics, and sustainability.
As Spain’s entrepreneurial ecosystem continues to thrive, here are 20 Spanish startups set to disrupt industries and drive the future of tech.
1. Métrica6: A Spanish Startup Redefining Engineering Excellence Through Innovation
Founded in 2018, Métrica6 is an engineering firm at the forefront of technological advancement. Specializing in product development and cutting-edge innovation, the company offers comprehensive R&D and consulting services to meet the unique needs of each client. Métrica6 stands out for its expertise in both hardware and software, seamlessly guiding clients through every stage of the product journey—from initial concept and prototyping to industrialization and successful market entry. With a passion for innovation, Métrica6 helps turn visionary ideas into impactful, market-ready products.
2. Foliume: Revolutionizing Insurance Marketing with AI
Foliume is an AI-driven marketing automation Spanish startup platform crafted specifically for insurance distribution businesses. Delivered as a Software as a Service (SaaS), it harnesses the power of data to elevate marketing strategies. In an era where insurance distributors are flooded with customer information, Foliume helps transform this data into targeted, personalized campaigns that boost customer retention and cross-selling opportunities. By leveraging advanced AI, Foliume empowers businesses to unlock the full potential of their data and create smarter, more effective marketing strategies.
3. Barbara: Empowering Industries with Edge AI for Unmatched Privacy and Speed
Barbara’s Edge AI platform is transforming the way businesses deploy and manage AI models, offering a level of privacy, autonomy, and real-time performance that traditional cloud systems can’t match. Tailored for industries requiring rapid responses and robust security, Barbara has become the trusted solution for energy distributors, infrastructure managers, logistics operators, and manufacturers. With Barbara, companies can harness the full power of AI while maintaining control and ensuring data protection, all in real-time.
4. Beseif CORE: Revolutionizing eCommerce with Seamless Automation
Beseif CORE is an advanced automation platform designed to optimize eCommerce operations. Automating essential tasks like payments, shipping, billing, and customer communications, boosts efficiency and cuts down on manual effort. With Beseif CORE, businesses gain access to a powerful infrastructure that effortlessly integrates with over 60 applications, simplifying workflows and ensuring smooth, hassle-free operations with just a single click.
5. Quibim: Pioneering the Future of Medical Imaging and Diagnostics
Headquartered in Valencia, Spain, Quibim is a global trailblazer in whole-body medical imaging analysis, revolutionizing how healthcare interprets and leverages imaging data. Their innovative products are transforming diagnostic accuracy and treatment efficacy, empowering research and clinical teams worldwide. At the core of Quibim’s groundbreaking solutions is Quibim Precision®, a CE-marked, comprehensive imaging ecosystem designed for diverse applications, including disease detection and monitoring the effectiveness of new therapies. Quibim is setting new standards in precision healthcare, improving outcomes one scan at a time.
6. Nabrawind Technologies: Innovating the Future of Wind Energy
Nabrawind Technologies is at the forefront of revolutionizing wind turbine technology, driven by a commitment to innovation. Their mission focuses on three key objectives: lowering energy costs, overcoming logistical barriers that hinder the expansion of onshore wind turbines, and enhancing the strength and reliability of components using proven technologies. By achieving these goals, Nabrawind is pushing the boundaries of wind energy efficiency and sustainability, making a significant impact on the global transition to renewable energy solutions.
7. Nanoligent: Pioneering a Breakthrough in Cancer Treatment
Nanoligent is advancing drug discovery at the preclinical stage with a groundbreaking platform designed to target and eliminate CXCR4+ cancer cells. These cells, associated with highly aggressive cancers, are found in over 40% of patients across 23 cancer types. Acting like Cancer Stem Cells (CSCs), CXCR4+ cells are key drivers of metastasis, tumor relapse, and resistance to conventional therapies such as chemotherapy and radiotherapy. By focusing on these challenging cancers, Nanoligent’s innovative approach offers new hope for patients with difficult prognoses, aiming to address the root causes of cancer spread and recurrence.
8. Mediktor: Revolutionizing Healthcare with AI-Powered Triage and Pre-Diagnosis
Mediktor is the leading AI-driven medical chatbot, transforming the way patients navigate healthcare. It intelligently directs individuals to the right level of care, enhancing accessibility and simplifying the process for both patients and healthcare providers. With its sophisticated AI engine, Mediktor supports natural, multilingual communication, making healthcare more efficient and user-friendly. Offering a white-labeled SaaS platform, Mediktor is fully omnichannel, easily integrating into any web, mobile, or desktop interface to ensure seamless healthcare experiences.
9. Factorial: Simplifying HR Management for SMBs with All-in-One Software
Factorial offers a robust, free HR software solution designed specifically for small and medium-sized businesses worldwide. It simplifies key HR functions like employee management, time tracking, and payroll, all in one seamless platform. Additionally, it provides a wide array of employee benefits, including health insurance, meal vouchers, and gym memberships. By combining powerful HR tools with customizable perks, Factorial streamlines operations and boosts employee satisfaction, making HR management easier and more efficient for businesses of all sizes.
10. Zinklar: Revolutionizing Consumer Insights for Brands Worldwide
Zinklar is a cutting-edge platform that empowers brands to instantly uncover consumer preferences with ease. With its user-friendly interface, Zinklar connects businesses to a vast pool of over 140 million consumers across 80+ countries, providing actionable insights in just hours. By accelerating the research process, Zinklar enables businesses to conduct up to 15 times more surveys than traditional methods, helping them stay ahead of the curve with fast, data-driven decisions.
11. Mitiga Solutions: Harnessing Science and AI to Tackle Climate Risk
Launched in 2018, Mitiga Solutions is revolutionizing climate risk management with cutting-edge science, AI, and supercomputing power. Their innovative platform, EarthScan™, enables businesses to detect, report, and mitigate climate risks in a self-service format. With a mission to enhance global resilience in the face of escalating climate challenges, Mitiga provides actionable insights that empower companies to make informed decisions and adapt proactively to environmental shifts.
12. Holded: Streamlining Business Management Across All Devices
Holded is an intuitive management software that simplifies how businesses operate, accessible on iPhone, Android, the web, and even Mac computers. With its sleek design and powerful features, Holded allows users to manage tasks seamlessly across all devices, boosting efficiency and productivity. By integrating with popular apps and services, Holded amplifies its functionality, making it the ultimate all-in-one solution to keep your business organized and running smoothly. Work smarter, faster, and more effectively with everything you need in one place.
13. YBVR: Redefining Live Experiences with Immersive VR and 360° Streaming
Based in Silicon Valley, YBVR is a cutting-edge tech startup that’s transforming the way fans experience live events. Specializing in next-gen virtual reality (VR) and 360-degree broadcasting, YBVR offers sports and concert enthusiasts immersive experiences that transport them into the heart of the action. Whether on mobile, web, or XR devices, their technology delivers breathtaking 8K live streaming at 60 frames per second, setting a new standard for visual quality. YBVR is revolutionizing the way we connect with live entertainment, bringing events to life like never before.
14. Nuclia: Empowering Smart, Meaningful Search Experiences
Nuclia is redefining how users build search engines by focusing on understanding context and making searches more accurate and intuitive. For developers, Nuclia offers an open-source SDK that allows for the creation of custom front-end interfaces or the integration of advanced search features into existing systems. By streamlining data indexing and search functionality, Nuclia enables businesses to deliver exceptional, smart search experiences that truly meet user needs.
15. ARTHEx Biotech: Innovating RNA-Based Therapies for a Healthier Future
Born out of the University of Valencia, ARTHEx Biotech is pioneering groundbreaking oligonucleotide therapies that target microRNA to address diseases in need of new solutions. Their innovative ENTRY platform allows for the rapid and flexible design of miR-modulating oligonucleotides, advancing the development of targeted treatments. With a focus on precision and adaptability, ARTHEx is pushing the boundaries of biotech to offer cutting-edge therapies for complex medical challenges.
16. Colvin: Revolutionizing the European Floral Industry with Freshness and Sustainability
Founded in Barcelona, Colvin is a bold new startup aiming to transform the €30 billion European floral market. Their innovative approach creates a direct marketplace connecting buyers with flower growers, cutting out the middlemen to deliver fresher flowers at lower prices. With a chic brand and seamless customer experience, Colvin is all set to bloom. Not only do they offer longer-lasting flowers, but their model also benefits the planet, promoting sustainability along the way. It’s a fresh take on florals—good for you, your wallet, and the Earth.
17. Twinco Capital: Revolutionizing Supply Chain Finance for Smarter Growth
Twinco Capital is a forward-thinking fintech company dedicated to transforming supply chain finance. With innovative platforms and services designed to optimize working capital and simplify cash flow, they provide businesses with the tools they need to thrive. Their solutions—ranging from invoice financing and inventory management to credit risk assessment—empower companies to boost liquidity, reduce financial friction, and scale operations with greater efficiency. Twinco Capital is helping businesses unlock their full potential through smarter, more fluid financial management.
18. Eranovum: Accelerating the Shift to Renewable Energy and Sustainable Mobility
Founded in 2019, Eranovum is driving the transition to a greener future by focusing on renewable energy, self-consumption, and electromobility. As an independent energy producer, the company invests in solar power, wind energy, and advanced storage solutions. Eranovum goes beyond energy production, providing integrated EV charging infrastructure for real estate partners, enabling the growth of sustainable mobility. By managing the full value chain—from energy generation to delivery—Eranovum ensures that electric vehicle users enjoy 100% renewable energy, making a powerful impact on the clean energy and e-mobility sectors.
19. Kibus: The Future of Pet Nutrition with IoT-Powered Meal Prep
Kibus introduces the world’s first IoT-enabled device that effortlessly prepares fresh, nutritious meals for dogs. Designed for convenience, it allows pet owners to easily provide a wholesome, natural diet for their furry companions. Simply add water and Kibus’ exclusive food recipes once a week, and with the push of a button, the device takes care of the cooking, delivering freshly prepared meals daily. It’s a game-changer in pet care, combining innovation and nutrition for your dog’s well-being.
20. IGNIS: Pioneering Sustainable Solutions for a Greener Future
IGNIS is a forward-thinking company at the forefront of renewable energy and environmental conservation. Specializing in cutting-edge technologies for energy storage and eco-friendly solutions, IGNIS is committed to tackling global challenges like climate change and resource depletion. Through its strong focus on research and development, the company delivers scalable, efficient innovations that pave the way for a cleaner, more sustainable world. IGNIS is leading the charge toward a greener future, with solutions designed to transform the energy landscape and safeguard our planet.
Conclusion
These 20 Spanish startups are leading the way in technology, sustainability, and innovation, poised to make a significant impact across various industries. With their groundbreaking solutions, these companies are shaping the future of Spain’s startup ecosystem and contributing to a more sustainable, efficient world.
